"Holmes Agency" is a private detective office known as the "Big-Eating" Detective Office. Seiya Takano (Noriyuki Higashiyama), who is known for have a huge appetite, gets assigned to this office as the new leader. Ryosuke Noda (Go Morita) and Ryoko Izumi (Mikako Ichikawa), both also having a big appetite work under Seiya. Murder, robbery, and kidnapping - many incidents occur around them. And the three solve each of the many cases in a most surprising way - their appetite results in marvelous speculations! They eat at the murder scene. They eat on the track. They even eat dog food! They keep on eating and eating, not even listening to the witness. Everywhere they go, they eat and eat and eat! And every time after finishing, the criminal appears. KUITAN is the words "Big-Eating (KUIshinbo)" and Detective (TANtei) combined together. "Real Gourmet" plus "Real Mystery". The big-eating detectives are on the run, solving cases from their deep knowledge about food. "KUITAN"- a new type of mystery drama you'll sure enjoy!

热闹非凡的「美食王」侦探事务所--「福尔摩斯代理店」。
新上任的头儿高野圣也（东山纪之饰）是个极端美食主义者。两个大肚汉的部下，野田凉介（森田刚饰）和出水京子（市川实日子饰），也几乎是每天「My 筷子」不离手。
三人被卷入各种各样的杀人、强盗、诱拐・・・事件之中。但令人惊奇的是，通过他们巨大的食欲和异想天开的新鲜推理术，事件一个一个被揭开谜底。
杀人现场・・・吃！跟踪途中・・・吃！狗粮・・・照样吃！调查取证・・・先吃再说！吃！ 吃！吃！ 吃尽一切！于是在吃光所有的东西之后出现在眼前的是・・・真正的犯人！
对！「用美食来侦察」就是「美食王」的策略。
「经典的美食情报」＋「经典的侦察」。热闹的「美食侦探」们利用点点滴滴的美食知识展开缜密细致的推理！新型推理电视剧从此诞生！