"Call me CA!" tells the story of a 28-year-old, single domestic airline CA (cabin attendant), Sae Yamada (Arisa Mizuki), looking for love and fulfillment in life...well not really. She's looking for love, PERIOD! Five years ago, her high school sweetheart was snatched from her grasp by a CA. That's what prompted her to pursue a career as a CA despite of having no interest in the profession itself. In the air, Sae experiences losing altitude of self esteem by repeating bungles, and is ordered time and time again to write letters of apology by her boss. On the ground, Sae devotes her full attention to attending 'Go-kon' (group blind date, the ritual which fuels the social life of Japanese singles). But on one of these Go-kons, Sae finds a younger, prettier colleague,who snubbed Sae's idea of showing up wearing their killer uniforms. Sae learns a lesson about the rules of survival in the love jungle; there are no rules! And if that isn’t enough, she is constantly looked down by nasty international CAs. But Sae shows cheerful resilience, or even talent for navigating the girls through fighting against common enemies such as womanizers specializing in CAs. Still Sae has difficulty expressing her honest feelings to a handsome pilot (Shosuke Tanihara), saying spiteful things,which only leads into their perpetual quarrel. You might call it the foreplay of a relationship.Through her bumpy flight, Sae is gradually learning that happiness is something not given by others, but grasped by oneself. Can Sae spread her wings as a CA, and succeed the soft landing of love?

主人公的山田纱依（观月亚理纱）二十八岁，独身。职业，国内航线的Cabin Attendant（空姐），简称CA。

五年前在便当店打工的纱依，被身着CA制服的女性夺走了恋人。纱依一气之下，猛学习，决意要考上CA！成为人见人爱，另女性羡慕的白领女性，气死甩她而去的恋人，让他悔不痛生！而且做CA还可以享受到优雅的物质生活···

当梦寐以求的CA制服着身之后，她才发现，那只不过是空中的体力劳动者。而且由于工作上的不断失误，使时薪制的契约社员升正式社员的希望也越发开始渺茫。陈旧狭窄的职工宿舍生活···这现实离想像太遥远了！于是纱依把赌注押在相亲派对上，指望着麻雀变凤凰。但好时机总是被那些为恋爱而不择手段的后辈抢占鳌头。工作中又受傲慢的国际航线CA们所蔑视，简直就没有顺心的事！与英俊驾驶员高冈真（谷原章介）可为爱憎不明的冤家对头，彼此挖苦讽刺，风凉话不断。

渐渐地，在与同样脆弱的同事们的相处与竞争中，纱依终于明白了。
我的幸福，用我自己的这双手来寻找、抓牢！
恋爱与事业悬崖岌岌可危的二十八岁，纱依能顺利地抓住自己的幸福吗？